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Can a Dog Overdose on Trazodone? (Answered 2023)

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Can a dog overdose on trazodoneWe’ve all heard the saying prevention is better than cure, and when it comes to Trazodone, an antidepressant medication for dogs, that couldn’t be truer. With more trazodone being prescribed for treating anxiety-related behavioral issues in canines, pet owners must understand what happens if their dog accidentally ingests this drug—and how to recognize overdose symptoms of trazodone in order to prevent a serious health crisis.

Can a Dog Overdose on Trazodone? This article will provide information about the safety and recommended dosage of trazodone as well as potential side effects and interactions with other drugs so that you are informed enough to keep your pup safe from harm’s way.

Key Takeaways

  • Trazodone is prescribed for dogs to treat anxiety and behavioral issues.
  • Trazodone can cause sedation, vomiting, diarrhea, and rarely, agitation as side effects.
  • Overdose symptoms of trazodone in dogs include tremors, seizures, and agitation.
  • Trazodone should not be given to dogs with certain health conditions and can interact with other medications.

Is Trazodone Safe for Dogs?

Is Trazodone Safe for Dogs
You’ll want to be extra careful with that bottle of Trazodone if your pup’s around, as too much can really do a number on them. Trazodone is generally safe when given at the proper dosage prescribed by your vet.

However, overdosing can cause dangerous side effects like agitation, vomiting, diarrhea, tremors, seizures, and even death in severe cases.

That’s why it’s critical to follow dosage guidelines and keep the medication safely secured. Tell your vet about any side effects you notice after starting Trazodone, like increased anxiety or lethargy, so they can adjust the dosage if needed.

And never give your dog Trazodone that wasn’t prescribed specifically for them, as dosages vary widely depending on the dog’s size and condition.

With some care and caution, Trazodone can help provide much-needed calm for anxious pups. But an overdose can quickly lead to toxicity, so safe storage and dosage vigilance are a must.

What is Trazodone Used for in Dogs?

What is Trazodone Used for in Dogs
Trazodone is prescribed for dogs to treat anxiety and behavioral issues, such as fear of loud noises, separation anxiety, and aggression. For example, a fearful rescue dog’s thunderstorm phobia improved with trazodone and behavior modification.

Veterinarians may prescribe trazodone for dogs with anxiety issues like fear of thunder, fireworks, vet visits, being alone, or aggression towards other dogs or people. It can help dogs respond better to training and behavior modification techniques.

The dosage of trazodone is tailored to your dog’s size and symptoms, usually 1-5 mg per kg given 1-3 times daily. Potential side effects of trazodone in dogs include sedation, vomiting, and diarrhea. In rare cases, dogs may become agitated. It is important to note that high doses of trazodone can lead to serotonin syndrome, which can cause tremors, seizures, and even death.

Therefore, it is crucial to never exceed the prescribed dosage and to keep trazodone secured to prevent accidental ingestion.

Overall, with proper veterinary guidance, trazodone can greatly help anxious dogs. However, it is important to be vigilant about dosage and potential toxicity if accidentally ingested.

When Can Dogs Be Given Trazodone?

When Can Dogs Be Given Trazodone
Don’t give it if your pup has liver or kidney disease, low blood pressure, or has had a seizure.

There are some cases when trazodone should not be administered to dogs:

  1. If your dog has liver or kidney problems. Trazodone is metabolized by the liver, so impaired function can lead to toxicity.
  2. If your dog has low blood pressure. Trazodone can lower blood pressure further.
  3. If your dog has a history of seizures. Trazodone can lower the seizure threshold.
  4. If your dog is taking other drugs that affect serotonin levels. This increases the risk of serotonin syndrome.

Carefully go over your dog’s medical history with your vet before starting trazodone.

There are alternatives for anxiety, like pheromones, CBD oil, and behavioral training. However, trazodone can be very helpful when used properly under veterinary supervision.

Monitor your dog closely and contact your vet with any concerns.

What is the Recommended Dosage of Trazodone for Dogs
Trazodone dosage in dogs requires careful consideration as there is a potential for overdose. The recommended dosage is 1-5 mg per pound given 1-3 times daily, but this depends on your dog’s anxiety levels and response to treatment.

It’s crucial to monitor your dog closely and consult your vet, as trazodone can interact with other medications, and high doses can be toxic.

Can Dogs Overdose on Trazodone?

Look alive, accidents happen when people get careless about keeping medications secured. Trazodone overdoses in dogs can cause tremors, seizures, and even death. If ingestion occurs, contact your vet immediately; they will advise on inducing vomiting and hospitalization if necessary.

Preventing drug exposure keeps your pup safe. Watch for concerning symptoms and side effects. With veterinary assistance, dogs can recover from trazodone ingestion. Stay vigilant and keep medications out of reach.

Can Trazodone Be Given to Dogs Daily?

You’ll be glad to know trazodone can be given to your pup daily if their vet prescribes it for chronic anxiety or behavioral issues.

However, long-term use does require caution. Consult your vet about alternatives if concerns arise.

Other Medications and Dosages for Dogs

You’d be prudent to consult your veterinarian on suitable medicine and doses for your pooch’s needs. Trazodone alternatives like fluoxetine or amitriptyline may better suit your dog. Follow prescribing guidelines for canine dosing, watch for drug interactions, and monitor your pet closely.

Certain medications like benzodiazepines carry addiction risks. Work with your vet to find the safest approach for managing your dog’s anxiety, whether situational or chronic. Regular check-ups ensure proper med use, effectiveness, and early detection of side effects like serotonin syndrome.

With care and vigilance, medications can greatly improve your dog’s quality of life.

What Are the Side Effects of Trazodone in Dogs?

What Are the Side Effects of Trazodone in Dogs
For dogs, possible side effects of trazodone include sedation, lethargy, vomiting, diarrhea, and coordination issues. These side effects often result from an excessive dose. Consult your vet about proper dosage guidelines for your dog’s weight, health status, and condition being treated.

Overdoses manifest in more severe symptoms like high heart rate, trembling, seizures, and even death. If you suspect trazodone overdose, contact your vet immediately. They’ll advise on possible treatment options like induced vomiting, activated charcoal, sedation, or hospitalization for monitoring.

To prevent accidental overdoses, keep medications secured and out of your dog’s reach. Inform houseguests. With proper veterinary guidance, trazodone can safely and effectively treat dog anxiety and behavior issues without complications.

How Long Does It Take for Trazodone to Calm a Dog?

How Long Does It Take for Trazodone to Calm a Dog
It won’t take too long for the trazodone to start working its magic on your nervous pooch.

When given as prescribed by your veterinarian or veterinary behaviorist, you can expect trazodone to begin calming your anxious dog within:

  • 30 minutes if given on an empty stomach
  • 1 hour if given with a meal
  • 2 hours for maximum effects to emerge
  • 6-8 hours for sedative effects to wear off
  • 24 hours for the medication to fully clear their system

The timing will vary based on factors like your dog’s size, metabolism, dosage, and whether it’s their first time taking trazodone. Be patient, let the medication take effect, and focus on keeping your dog comfortable and secure as their anxiety subsides.

With proper use under veterinary supervision, trazodone can safely ease your dog’s stress and worries.

Recognizing Trazodone Overdose Symptoms in Dogs

Recognizing Trazodone Overdose Symptoms in Dogs
You’ll detect an overdose by noticing unusual behaviors like tremors, seizures, or losing coordination.

  • Agitation or restlessness
  • Dilated pupils
  • Drooling or foaming at the mouth
  • Lethargy or lack of coordination
  • Muscle tremors or seizures

If you spot any of these signs, take emergency action. Contact your vet or an emergency animal hospital right away. They can provide prompt treatment to stabilize your dog and prevent lasting harm. Options may include inducing vomiting, giving activated charcoal, administering IV fluids, controlling blood pressure, and preventing seizures.

Having the right information empowers you to take quick, decisive steps if an accidental overdose occurs. Stay vigilant about medications and keep them secured. Your attentiveness ensures your beloved companion stays happy and healthy.

Treatment for Trazodone Overdose in Dogs

Treatment for Trazodone Overdose in Dogs
Call your vet right away if you notice your pup acting strange after getting into meds. They’ll advise on inducing vomiting or giving activated charcoal to prevent absorption, monitor symptoms, and provide supportive care like IV fluids and seizure meds if needed.

Trazodone toxicity requires emergency veterinary response. Look for symptoms like agitation, tremors, diarrhea, vomiting, seizures, or anything out of the ordinary and contact your vet immediately. They’ll assess and monitor for serotonin syndrome and determine the best course – including inducing vomiting if appropriate, giving activated charcoal to prevent further absorption, hospitalizing for supportive care with IV fluids and medications to control blood pressure, heart rate, and seizures.

Preventing access to medications is best, but swift action is critical in cases of canine trazodone overdose. Your vet is your best resource for specific treatment and monitoring to address this potentially life-threatening toxicity.

Drug Interactions and Warnings for Trazodone in Dogs

Drug Interactions and Warnings for Trazodone in Dogs
Let’s be cautious when it comes to your pup’s medication and make sure there are no interactions with other treatments. Trazodone can interact with many medications and supplements, so it’s important to inform your vet about everything your dog takes.

  1. Anti-anxiety meds like alprazolam or fluoxetine.
  2. Pain relievers like tramadol or carprofen.
  3. Anticonvulsants for seizures like phenobarbital.
  4. Antibiotics like chloramphenicol.
  5. Supplements like melatonin or 5-HTP.

Combining trazodone with drugs that affect serotonin levels can lead to serotonin syndrome, which is a life-threatening condition. It can cause high fever, tremors, seizures, and other severe symptoms that require emergency veterinary care.

It’s crucial to stay vigilant about drug interactions and follow your vet’s guidance to prevent the risks of overmedication.

Preventing Trazodone Exposure and Accidental Ingestion

Preventing Trazodone Exposure and Accidental Ingestion
You must secure medications and belongings from your pet’s reach, as well as alert houseguests, to prevent accidental ingestion that could be harmful. Medications should be stored in child-proof or pet-proof containers, up and away from your dog’s access.

Purses, bags, and coats with medications or other dangerous items inside should be placed out of reach, even during short visits. Ask visitors to stow their belongings safely. Make it a habit to scan for and pick up any dropped pills immediately.

Keep trash cans covered or behind closed doors, as dogs can tip them over and ingest hazardous waste.

Location: Counters

Storage Tips: Keep medications in high cabinets or drawers your dog cannot access.

Location: Bedside Tables

Storage Tips: Use child locks or secure in a drawer. Never leave pills openly accessible.

Location: Purses

Storage Tips: Hang purses on hooks high up or place in a closet with the door shut.

Location: Coats

Storage Tips: Place coats in a closet or use hooks too high for your dog to reach.

Location: Trash

Storage Tips: Use lidded cans stored out of reach. Take trash out frequently.


When it comes to your four-legged friend, you want to make sure they’re always safe and healthy. Trazodone can be a useful tool in managing anxiety and behavioral issues in dogs, but unfortunately, an accidental overdose can have serious consequences.

So, can a dog overdose on trazodone? Yes, they can. Toxicity in dogs depends on the amount ingested relative to their body weight, and high doses can be fatal.

Common side effects of trazodone ingestion in dogs include agitation, drooling, tremors, and seizures.

To prevent drug exposure and accidental ingestion, store medications out of reach, watch for signs of distress, and contact your vet immediately if you notice abnormalities.

With the right precautions, you can help keep your furry companion safe and sound.

Avatar for Mutasim Sweileh

Mutasim Sweileh

Mutasim is an author and software engineer from the United States, I and a group of experts made this blog with the aim of answering all the unanswered questions to help as many people as possible.